About

I am a Ph.D Candidate in Biology (Computional Biology) at the School of Life Sciences, Westlake University, advised by Prof Weike Pei & Prof Yanxiao Zhang. Before i joined Westlake University, I worked with Professor Jie Wang at Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences.

I am also an amateur bodybuilder with 125KG maximal weight for bench press, 180KG maximal weight for Deadlift, and 170KG maximal weight for Squat.

📡 Research Interset

• Developing computational tools for single-cell genomics and spatial genomics
• Constructing large-scale cell atlas based on cutting-edge sequencing technologies
• Investigating regulatory mechanisms in cell fate decision and disease occurrence

🚩 Professional Experience in Computional Biology

• Ph.d Candidate in Biology (Computional Biology) at Westlake University. 2022.08-present

• Research Assistant at Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences. 2021.03-2022.06 (Get computational biology training here, with great gratitude to Professor Jie Wang)

• Bioinformatician Intern at Singleron Biotech. 2020.12-2021.02 (Just run pipeline, boring……)

• Master in Genomics & Bioinformatics at Chinese University of Hong Kong. 2020.09-2021.11 (Where my bioinformatics journey begin)

📝 Selected Publications

*: co-first, #: correspondence

scLTdb: a comprehensive single cell lineage tracing database Junyao Jiang*, Xing Ye*, Yunhui Kong*, Chenyu Guo, Mingyuan Zhang, Fang Cao, Yanxiao Zhang#, Weike Pei# Nucleic Acids Research, Oct 2024, IF 16.6 Keywords: Single cell genomics, Lineage tracing, Cell fate

CACIMAR: cross-species analysis of cell identities, markers, regulations, and interactions using single-cell RNA sequencing data Junyao Jiang*, Jinlian Li*, Sunan Huang, Fan Jiang, Yanran Liang, Xueli Xu#, Jie Wang# Briefing in Bioinformatics, June 2024, IF 9.5 Keywords: Single cell genomics, Cross-species analysis

IReNA: Integrated Regulatory Network Analysis of Single-Cell Transcriptomes and Chromatin Accessibility Profiles Junyao Jiang*, Pin Lyu*, Sunan Huang, Jiawang Tao, Seth Blackshaw, Qian Jiang, Jie Wang iscience, Oct 2022, IF 6.1 Keywords: Single cell genomics, Gene regulatory network

📝 Other Publications

Yunhui Kong*, Junyao Jiang*,#, Weikang Kong, Sheng Qin#. DRCTdb: disease-related cell type analysis to decode cell type effect and underlying regulatory mechanisms. Communications Biology, Sep 2024 (Co-first & Co-correspondence)

Ying Xin*, Pin Lyu*, Junyao Jiang, Fengquan Zhou, Jie Wang, Seth Blackshaw, Jiang Qian. LRLoop: Feedback loops as a design principle of cell-cell communication. Bioinformatics, July 2022

Dapeng Sun*, Xiaojie Gan*, Lei Liu*, Yuan Yang*, Dongyang Ding, Wen Li, Junyao Jiang, et al. DNA hypermethylation modification promotes the development of hepatocellular carcinoma by depressing the tumor suppressor gene ZNF334. Cell Death & Disease, May 2022

🀄 Award

• 2024 National Scholarship

💻 Maintained Software

• IReNA Consturct gene regualtory networks based on single cell multiomics data
• CACIMAR scRNA-seq based cross-species data analysis
• FateMapper single cell lineage tracing data analysis and visualization
• scLTdb Database for single cell lineage tracing

📛 Mentorship

Xing Ye: Undergraduate from University of Science and Technology of China, 2023.11-2024.06. (Co-first author at scLTdb project)